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Fig. 7. Comparisons of the predicted amino acid sequence of zebrafish HSF with those of human HSF1, mouse HSF1, chicken HSF1, and rainbow trout HSF1a proteins. Residues identical to the amino acid in the zebrafish HSF (accession number AB062117) are indicated by dots. Amino acids that are present in zebrafish HSF, but not in other HSFs, are marked by dashes. The regions boxed with a solid line or broken line indicate the predicted DNA binding domains and hydrophobic heptad repeats, respectively. The potent heat-activation domain boxed in red is suggested to regulate temperature ranges for HSF activation and conformational changes.

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