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Fig. 6. The nucleotide sequence of the 5'-upstream region of the zebrafish hsp70-a gene. The transciption start site was determined by primer extension. The nucleotide sequences in exons are underlined. The zebrafish hsp70 gene contains only one intron in the 5'-noncoding region. The translation start ATG codon is in italics. The heat-inducible expression of the zebrafish hsp70 gene is suggested to be regulated by a dual promoter system, i.e., a heat-shock promoter containing HSE upstream of the transcription start site and another constitutive promoter in the first intron (Yabu et al. unpublished).

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