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Fig. 4. Molecular phylogenic tree of the HSP70 family members. Amino acid sequences of the vertebrate HSP70s were compared by the neighbor-joining method with the CLUSTAL W program (version 1.83). Bootstrap confidence values for the sequence groupings are indicated in the tree (n = 1000). The scale indicates the evolutionary distance of one amino acid substitution per site. Sequence database accession numbers in GenBank or genomic contig scaffold numbers in the zebrafish and Takifugu Ensenbl Genome Servers are indicated in parentheses.

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