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Fig. 37. Electron micrograph of hepatocytes from Takifugu poecilonotus. (a) There are three hepatocytes in the electron micrographs. Each cell contain many microorganism-like components (arrows). No abnormal bioreactions are seen in every hepatocyte. F, fat droplet. Bar = 2 μm. (b) Enlarged part of (a). Three round microorganisms are seen. These are surrounded by double membranes from the cytoplasms of the hepatocytes. Numerous ribosomes (R) and the thick septum (S) are demonstrable. Bar = 0.5 μm. Reprinted with permission from Kodama, Shimizu, Sato, Ogata and Terao. The infection of bacteria in the liver cells of toxic puffer—A possible cause for organisms to be made toxic by tetrodotoxin in association with bacteria. Harmful Marine Algal BloomsProceed. 6th Intern. Conference Toxic Marine Phytoplankton, Nantes, October 1993, P. Lassus et al., © Technnique et DocumentationLavoisier, 1995.

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